Comparison of indoor air quality and thermal comfort standards and variations in exceedance for school buildings

Addressing indoor air quality (IAQ) and thermal comfort issues in school buildings is challenging but relevant. Firstly, their primary occupants are more vulnerable than adults. Secondly, school buildings are often inadequate being too old or designed to prioritise energy-efficiency targets. Thirdly, occupants have often little control over the indoor environmental quality (IEQ). Lastly, the SARS-CoV-2 pandemic highlighted the complexity and vulnerability of existing decision-making processes in relation to making timely and well-informed decisions about IEQ threats. Standards and guidelines vary over time and among similar countries despite targeting similar occupants, evaluate IAQ and thermal comfort independently, and do not include any specific adaptations to children. Thus, the aim of this research is to compare different available standards to evaluate IAQ and thermal comfort in school buildings. By analysing with different standards (EN16798, BB101, and ASHRAE 55 and 62.1) the data collected in schools in northern Italy, this research evaluated the consequences of different limits and approaches, and proposed improvements. The conclusions are that (i) thresholds and methods inconsistency within the same standard should be avoided;(ii) upper- and lower-bounded operative temperature scales are the most appropriate means to design and verify thermal comfort in classrooms;(iii) IAQ metrics that give an upper limit per a certain amount of consecutive time might prevent the build-up of indoor pollutants, even with high emissions from the building fabric;(iv) no standard proposes a combined IAQ and thermal comfort analysis which could enable more informed trade-off decisions considering IAQ, thermal comfort, and energy targets. © 2023 The Authors

TIME SERIES ANALYSIS OF METEOROLOGICAL PARAMETERS AND AIR POLLUTION CONCENTRATIONS IN EMILIA-ROMAGNA, ITALY, DURING COVID-19 INFECTION

During the pandemic, Italy experienced several phases of lockdown with different types of restrictions. Starting on February 23rd 2020, 11 municipalities in northern Italy suspended activities in schools, universities, museums, cultural venues, and all public initiatives. The ordinance announcing the national emergency was released on March 11th, stabilising the first lockdown period for the whole of Italy, which lasted until the second half of May. After a phase of cushioned restrictions during the summer, the so-called 'Second Wave' began forcing anew ordinance on October 13th with more stringent restrictions as the number of infections increased. On November 3rd, the "colour system" was introduced with three risk bands-red, orange and yellow-assigned weekly to the regions based on monitoring indicators. The main objective of the present study is to assess the impact of the meteorological and air quality conditions on COVID-19 cases in the region of Emilia-Romagna in Italy during the lockdown periods. Several pollutant time series from the Copernicus Atmosphere Monitoring Service were joined with meteorological data from the daily gridded land-only observational dataset over Europe and then compared with the total number of infections, hospitalisations and deaths. Data provided by the two monitoring systems were processed through an algorithm and organised by provinces and municipalities in Emilia-Romagna, Italy. The explorative analysis, conducted using both time series and seasonally adjusted time series, shows that pollutants most affected by lockdown phases are CO, NO2, PM10, PM2.5 and SO2. The findings in this study may help further studies better understand the variations 2020 and 2021 and the correlation with COVID-19 variables. © British Crown Copyright (2022)

From branding to solidarity: The COVID-19 impact on marketing Strachítunt cheese from Val Taleggio, Italy

Branding, labelling and certification are the principal instruments for marketing heritage cheese in the Italian Alps. However, the COVID-19 pandemic has put considerable strain on these tools. In Val Taleggio, where the Protected Designation of Origin cheese Strachítunt is made, the cooperative of pro-ducers suffered a breakdown in access to markets during the lockdown of March–May 2020. Their strategy was to appeal directly to consumers, connecting digitally with solidarity economy networks such as Gruppi di Acquisto Solidale (Solidarity Purchase Groups). Building on long-term ethnography, the article shows how this appeal brought to the surface a shared discourse and understanding of proximity and solidari-ty, which is not usually employed in the language of certification and labelling. © 2022, Zalozba ZRC. All rights reserved.

Preliminary Spatiotemporal Analysis of Mortality in Northern Italy During COVID-19 First Wave

We present a large-scale spatiotemporal analysis of excess mortality (EM) in the first COVID-19 epidemic wave in Lombardy and Veneto. Spatial statistics show that EM is spatially heterogenous in both regions. Global spatiotemporal correlation identifies EM trends that differ across regions during the epi-curve peak, but are uniform in early and late stages. Local spatiotemporal correlation identifies EM hotspots, coldspots, and transition zones. Identifying process dynamics and local features, spatiotemporal correlation can support epidemic surveillance. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

The Role of Information and Communication Technologies in Researching Older People During the Covid-19 Pandemic: The Case of the Italian Longitudinal Study on Older People’s Quality of Life During the Covid-19 Pandemic (ILQA-19)

The Longitudinal Study on Older People’s Quality of Life during the Covid-19 pandemic (ILQA-19) is a qualitative study carried out during the 2020 lockdown on 40 older men and women living in the ten villages in northern Italy subject to the first lockdown in Europe. This study focuses on older people’s lives and the role of digital technologies during the pandemic, and it has been carried out fully remotely. Despite the need to research the social consequence of pandemics for older people, there is a shortage of studies that provide guidelines on how to successfully involve this population in online qualitative studies. This paper contributes to fill this gap by discussing the use of Information and Communication Technology (ICT) in implementing the different stages of ILQA-19 research. The best practices of qualitative studies conducted through ICTs are discussed, along with the strategies we enacted to enhance participation in the study. Specifically, panel engagement, tailoring procedures and building positive and trustworthy interactions with study members are crucial when researching older people through online methods. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

Maternity ward management and COVID-19 pandemic: Experience of a single center in Northern Italy during lockdown.

INTRODUCTION: The aim of our study is to describe the management of a maternity ward in a referral center during the COVID-19 pandemic and 2020 lockdown. METHODS: This is a retrospective single-center study. We analyzed the records of all women consecutively admitted to our delivery ward during lockdown and compared them with those of women admitted in the same period in 2019. RESULTS: The number of patients (1260) admitted to our department in 2020 was similar (1215) to that in 2019. Among patients admitted during lockdown, 50 presented with a Sars-CoV-2 infection (3.9%). In 2020, the number of antenatal check-ups was lower than in 2019 [7.9 (1.5) vs 8.2 (1.3), p<0.001] and the rate of labor inductions was higher [436 (34.6) vs 378 (31.1), p=0.008] although no difference in delivery mode was found. Moreover, women admitted during lockdown were more likely to give birth alone [140 (11.1) vs 50 (4.1), p<0.001]. However, during 2020, the rate of mother and newborn skinto-skin contact [1036 (82.2) vs 897 (73.8), p<0.001] and that of breastfeeding within 2 hours from birth [1003 (79.6) vs 830 (68.3), p<0.001] was higher. We found no significant differences in maternal or neonatal outcomes. CONCLUSIONS: Despite the COVID-19 pandemic, we were able to guarantee a safe birth assistance to all pregnant women, both for those infected and those not infected by Sars-CoV-2.

COVID-19 After Lung Resection in Northern Italy.

We reviewed surgical cases from 4 Thoracic Surgery departments in the Lombardia region of Italy, the area mostly affected by Coronavirus pandemic in Europe, with the aim to describe the impact of COVID-19 on the treatment of thoracic surgical patients. Clinical, radiological and laboratory data from patients who underwent lung resection from December 2019 to March 2020 were retrospectively collected until June 2020. Univariable Cox regression models were estimated to evaluate potential prognostic factors for developing COVID-19 and to investigate postoperative mortality among patients who developed symptomatic COVID-19 infection. We examined data from 107 patients. (74 lobectomies, 32 wedge/segmentectomies and 1 pneumonectomy). Twelve patients developed COVID-19 (Group 1), whereas 95 patients were not infected (Group 2). In Group 1, 6 patients (50%) died from complications related to infection; in Group 2, one patient (1%) died because of non-COVID-19-related causes. Median days from surgery to first symptoms, CT confirmation, clinical confirmation and PCR positivity was 48.1, 54.3, 55.1, and 55.2 respectively. At univariable analysis, DLCO/VA% (P = 0.008), duration of the surgery (P = 0.009), smoking history (pack/year) (P < 0.001), BMI (P< 0.001) and number of segments resected (P = 0.010) were associated with COVID-19 onset. Moreover, CCI (P < 0.001), DLCO/VA% (P = 0.002), cigarette pack/year (P < 0.001), BMI (P < 0.001) and COVID-19 (P < 0.001) were associated with death. Patients who undergo lung resection and then develop symptomatic COVID-19 infection are at higher risk of developing severe respiratory complications and postoperative death. Insidious symptoms' onset may lead to a delay in diagnosis. We suggest two mitigating strategies: (1) Improve symptoms surveillance and isolation during recovery period, (2) Be aware of a potential greater risk of developing symptomatic COVID-19 and death correlated with elevated CCI, BMI, smoking history, DLCO/VA%, number of resected segments and duration of surgery.

A pre- and during Pandemic Survey of Sars-Cov-2 Infection in Stray Colony and Shelter Cats from a High Endemic Area of Northern Italy.

Cats are susceptible to infection with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). Whilst a number of studies have been performed worldwide on owned cats, limited data are available on stray, colony or shelter cats. We investigated SARS-CoV-2 infection in a stray cat population before and during human outbreaks of SARS-CoV-2 in cities in the Lombardy region in northern Italy, a high endemic region for SARS-CoV-2, using serological and molecular methods. A cohort of different samples were collected from 241 cats, including frozen archived serum samples from 136 cats collected before the 2019 coronavirus disease (COVID-19) pandemic and serum, pharyngeal and rectal swab samples from 105 cats collected during the SARS-CoV-2 outbreak. All pre-pandemic samples tested seronegative for antibodies against the nucleocapsid of SARS-CoV-2 using indirect enzyme linked immunosorbent assay (ELISA) test, while one serum sample collected during the pandemic was seropositive. No serological cross-reactivity was detected between SARS-CoV-2 antibodies and antibodies against feline enteric (FECV) and infectious peritonitis coronavirus (FIPC), Feline Immunodeficiency Virus (FIV), Feline Calicivirus (FCV), Feline Herpesvirus-1 (FHV-1), Feline Parvovirus (FPV), Leishmania infantum, Anaplasma phagocytophilum, Rickettsia spp., Toxoplasma gondii or Chlamydophila felis. No pharyngeal or rectal swab tested positive for SARS-CoV-2 RNA on real time reverse transcription-polymerase chain reaction (rRT-PCR). Our data show that SARS-CoV-2 did infect stray cats in Lombardy during the COVID-19 pandemic, but with lower prevalence than found in owned cats. This should alleviate public concerns about stray cats acting as SARS-CoV-2 carriers.

Management of gestational diabetes in women with a concurrent severe acute respiratory syndrome coronavirus 2 infection, experience of a single center in Northern Italy.

OBJECTIVE: In this study we describe the management of women with gestational diabetes (GD) and an ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aim of the study is to evaluate whether coronavirus disease 2019 (COVID-19) can further complicate pregnancies, and if the protocol we usually use for GD pregnancies is also applicable to patients who have contracted a SARS-CoV-2 infection. METHODS: This is a retrospective study analyzing all pregnant women with GD and concomitant COVID-19 admitted to our institution for antenatal care between March 1 and April 30, 2020. RESULTS: Among pregnant women with GD and a concomitant SARS-CoV-2 infection, the mean age was 32.9 (SD 5.6) years. Two patients (33%) were of white racial origin and four (67%) were of non-white racial origin. All patients were diagnosed with COVID-19 during the third trimester of pregnancy. Two women were asymptomatic and four were symptomatic. Only two (33.3%) women received treatment with insulin. None of the patients required intensive care or mechanical ventilation. No complications were found among the neonates. CONCLUSION: COVID-19 was not found to worsen the prognosis of patients with GD or of their offspring. Glycemic monitoring, diet therapy, and insulin, when needed, are sufficient for good metabolic control and favorable maternal and fetal outcomes.

Back to (new) normality-A CODRAL/AIRO-L survey on cancer radiotherapy in Lombardy during Italian COVID-19 phase 2.

BACKGROUND: Italy experienced one of the world's severest COVID-19 outbreak, with Lombardy being the most afflicted region. However, the imposed safety measures allowed to flatten the epidemic curve and hence to ease the restrictions and inaugurate, on the 4th of May 2020, the Italian phase (P) 2 of the pandemic. The present survey study, endorsed by CODRAL and AIRO-L, aimed to assess how radiotherapy (RT) departments in Lombardy have dealt with the recovery. MATERIALS AND METHODS: A questionnaire dealing with the management of pandemic was developed online and sent to all CODRAL Directors on the 10th of June 2020. Answers were collected in full anonymity one week after. RESULTS: All the 33 contacted RT facilities (100%) responded to the survey. Despite the scale of the pandemic, during P1 14 (42.4%) centres managed to safely continue the activity (≤ 10% reduction). During P2, 10 (30.3%) centres fully recovered and 14 (42.4%) reported an increase. Nonetheless, 6 (18.2%) declared no changes and, interestingly, 3 (9.1%) reduced activities. Overall, 21 centres (63.6%) reported suspected or positive cases within healthcare workforce since the beginning of the pandemic. Staff units were quarantined in 19 (57.6%) and 6 (18.2%) centres throughout P1 and P2, respectively. In the two phases, about two thirds centres registered positive or suspected cases amongst patients. CONCLUSION: The study revealed a particular attention to anti-contagion measures and a return to normal or even higher clinical workload in most RT centres in Lombardy, necessary to carry out current and previously deferred treatments.

A case series of novel coronavirus infection in heart transplantation from 2 centers in the pandemic area in the North of Italy.

BACKGROUND: Little is known about the coronavirus SARS-CoV-2 disease (COVID-19) in solid organ transplanted patients. We here report a series of heart transplanted patients with COVID-19 from two centers of Italy. METHODS: All heart transplanted patients of Transplant Centers of Bergamo and Torino with a microbiologically confirmed SARS-CoV-2 infection were enrolled. Data collection included clinical presentation, laboratory and radiological findings, treatment and outcome. Follow-up was performed by visit or phone. RESULTS: From February to March 2020 twenty-six heart transplanted patients (age 62±12 years; 77% males; time from transplant 10±10 years; 69% with comorbidities) had a microbiologically confirmed COVID-19. The most frequent symptom was fever, followed by cough. Seventeen patients had a pneumonia, 8 of them severe pneumonia. Seven patients died (27%) and 17 (65%) were hospitalized. Discontinuation of immunosuppression was associated with death (71 vs 21%, p=0.02). Conversely, all patients receiving steroids survived (p<0.001). Patients who received heart transplantation during COVID-19 outbreak survived and no acute graft rejection occurred. Patients who died were older than survivors, had a longer time from transplant and a worse clinical presentation at diagnosis. The current regimen enabled the prolonged survival and function of orthotopic cardiac xenografts in altogether 6 of 8 baboons, of which 4 were now added. These results exceed the threshold set by the Advisory Board of the International Society for Heart and Lung Transplantation. CONCLUSIONS: COVID-19 has a significant impact on long term heart transplanted patients. Conversely, SARS-CoV-2 infection seems to have a limited influence on more recent transplants. Our experience may suggest that heart transplantation programs can be maintained even during the pandemic phase if specific and tailored paths to prevent and to limit virus transmission are provided.